Veille documentaire MTPH

Médecine du travail du personnel hospitalier

Vaccination of health care workers to protect patients at increased risk for acute respiratory disease

Auteur     Gayle P Dolan
Auteur     Rebecca C Harris
Auteur     Mandy Clarkson
Auteur     Rachel Sokal
Auteur     Gemma Morgan
Auteur     Mitsuru Mukaigawara
Auteur     Hiroshi Horiuchi
Auteur     Rachel Hale
Auteur     Laura Stormont
Auteur     Laura Béchard-Evans
Auteur     Yi-Sheng Chao
Auteur     Sergey Eremin
Auteur     Sara Martins
Auteur     John S Tam
Auteur     Javier Peñalver
Auteur     Arina Zanuzadana
Auteur     Jonathan S Nguyen-Van-Tam
Résumé     Health care workers (HCWs) may transmit respiratory infection to patients. We assessed evidence for the effectiveness of vaccinating HCWs to provide indirect protection for patients at risk for severe or complicated disease after acute respiratory infection. We searched electronic health care databases and sources of gray literature by using a predefined strategy. Risk for bias was assessed by using validated tools, and results were synthesized by using a narrative approach. Seventeen of the 12,352 identified citations met the full inclusion criteria, and 3 additional articles were identified from reference or citation tracking. All considered influenza vaccination of HCWs, and most were conducted in long-term residential care settings. Consistency in the direction of effect was observed across several different outcome measures, suggesting a likely protective effect for patients in residential care settings. However, evidence was insufficient for us to confidently extrapolate this to other at-risk patient groups.
Publication     Emerging infectious diseases
Volume     18
Numéro     8
Pages     1225-1234
Date     Aug 2012

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doi:10.3201/eid1808.111355

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