Polyhexamethylenebiguanide hydrochloride exposure and erythema multiforme in a physician.
Int J Occup Med Environ Health. 2006;19(1):81-2.
Polyhexamethylenebiguanide hydrochloride exposure and erythema multiforme in a physician.
‘Gehanno JF, Priot AE, Balguerie X, Caillard JF.
Department of Occupational Medicine, Rouen University Hospital Charles Nicolle, Rouen, France.’
A 52-year-old woman physician developed recurrent erythema multiforme. Occupational and environmental exposure assessment suggested a disinfectant containing polyhexamethylenebiguanide hydrochloride (PHMB), Phagosept. Elimination of the product was followed by disappearance of symptomatology. Literature search revealed cases of sensitization and anaphylaxis due to contact with PHMB, but to our knowledge, this is the first report on PHMB-induced erythema multiforme.
‘MeSH Terms: Biguanides/adverse effects* – Erythema Multiforme/physiopathology* – Female – France – Humans – Middle Aged – Occupational Exposure – Physicians*
Substances: Biguanides; polyhexamethylene biguanide’
Publication Types: Case Reports
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