Preferred Label : Darbepoetin Alfa;

NCIt synonyms : Novel Erythropoiesis Stimulating Protein; NESP;

NCIT definition : A recombinant analog of the endogenous cytokine erythropoietin, an erythropoiesis-stimulating protein. Due to the addition of two carbohydrate chains, darbepoetin alfa exhibits a three-fold greater half-life than does erythropoietin. Similar to erythropoietin, darbopoietin alfa binds to and activates epoetin receptors, thereby inducing the differentiation and maturation of erythrocyte progenitors, stimulating endothelial cell proliferation, and stimulating B-cell proliferation and immunoglobulin production. (NCI04);

Alternative definition : NCI-GLOSS: A substance made in the laboratory that stimulates the bone marrow to produce red blood cells. It belongs to the family of drugs called antianemics.;

UNII : 15UQ94PT4P;

CAS number : 209810-58-2;

Drug name : Nespo; Aranesp;

NSC code : 729969;

Codes from synonyms : CDR0000256550;


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