Preferred Label : dextropropoxyphene;

MeSH definition : A narcotic analgesic structurally related to METHADONE. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect.;

MeSH synonym : d propoxyphene; propoxyphene; d-propoxyphene; hydrochloride, propoxyphene;

MeSH hyponym : propoxyphene phosphate, (S-(R*,S*))-Isomer; propoxyphene hydrochloride, (S-(R*,R*))-Isomer; propoxyphene hydrochloride, (R*,R*)-( -)-Isomer; darvon; propoxyphene hydrochloride; propoxyphene hydrochloride, (R-(R*,S*))-Isomer; propoxyphene hydrochloride, (R-(R*,R*))-Isomer; propoxyphene maleate, ( )-Isomer; propoxyphene sulfate, (S-(R*,S*))-Isomer;

Is substance : O;

UNII : S2F83W92TK;

Registry Number MeSH : 469-62-5; S2F83W92TK;

MeSH CAS label : benzeneethanol, alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (S-(R*,S*))-;

MeSH Related Number : propoxyphene hydrochloride; propoxyphene hydrochloride, (R*,R*)-( -)-Isomer; propoxyphene sulfate, (S-(R*,S*))-Isomer; propoxyphene hydrochloride, (R-(R*,S*))-Isomer; propoxyphene hydrochloride, (S-(R*,R*))-Isomer; propoxyphene maleate, ( )-Isomer; propoxyphene phosphate, (S-(R*,S*))-Isomer; propoxyphene hydrochloride, (R-(R*,R*))-Isomer; 104432-92-0 ((S-(R*,S*))-isomer, sulfate (salt)); 104432-93-1 ((S-(R*,S*))-isomer, phosphate (salt)); 1596-70-9 (HCl, (R-(R*,S*))-isomer); 1639-60-7 (Propoxyphene hydrochloride); 2338-40-1 (( )-isomer, maleate); 469-62-5 (Dextropropoxyphene); 6193-03-9 (HCl, (R*,R*)-( -)-isomer); 75044-79-0 (HCl, (S-(R*,R*))-isomer); 75044-80-3 (HCl, (R-(R*,R*))-isomer); 77-50-9 (cpd w/o isomeric designation); CB2TL9PS0T;

Related CAS MeSH : 6193-03-9 (Propoxyphene hydrochloride, (R*,R*)-( -)-Isomer); 104432-92-0 (Propoxyphene sulfate, (S-(R*,S*))-Isomer); 1596-70-9 (Propoxyphene hydrochloride, (R-(R*,S*))-Isomer); 75044-79-0 (Propoxyphene hydrochloride, (S-(R*,R*))-Isomer); 2338-40-1 (Propoxyphene maleate, ( )-Isomer); 104432-93-1 (Propoxyphene phosphate, (S-(R*,S*))-Isomer); 75044-80-3 (Propoxyphene hydrochloride, (R-(R*,R*))-Isomer); CB2TL9PS0T (Propoxyphene hydrochloride);

Codes EINECS : 207-420-5;

Details


Main resources

You can consult :

A narcotic analgesic structurally related to METHADONE. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect.

http://n2t.net/ark:/47881/m6v40ssp
2016
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false
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dissertations, academic
general practice
dextropropoxyphene
patients
general practitioners
has patient
generalized

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61771516
2012
France
summary of product characteristics
package leaflet
capsules
acetaminophen, dextropropoxyphene, drug combination
dextropropoxyphene

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66961932
2012
France
summary of product characteristics
package leaflet
acetaminophen, dextropropoxyphene, drug combination
capsules
dextropropoxyphene

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68229781
2012
France
summary of product characteristics
package leaflet
dextropropoxyphene
capsules
acetaminophen, dextropropoxyphene, drug combination

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61137309
2012
France
summary of product characteristics
package leaflet
capsules
dextropropoxyphene
acetaminophen, dextropropoxyphene, drug combination

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66078081
2012
France
summary of product characteristics
package leaflet
dextropropoxyphene
capsules
acetaminophen, dextropropoxyphene, drug combination

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69837651
2012
France
summary of product characteristics
package leaflet
capsules
dextropropoxyphene
acetaminophen, dextropropoxyphene, drug combination

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62665042
2012
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summary of product characteristics
package leaflet
acetaminophen, dextropropoxyphene, drug combination
capsules
dextropropoxyphene

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61921752
2012
France
summary of product characteristics
package leaflet
dextropropoxyphene
capsules
acetaminophen, dextropropoxyphene, drug combination

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64206504
2012
France
summary of product characteristics
package leaflet
capsules
acetaminophen, dextropropoxyphene, drug combination
dextropropoxyphene

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62666564
2012
France
summary of product characteristics
package leaflet
acetaminophen, dextropropoxyphene, drug combination
capsules
dextropropoxyphene

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61605537
2012
France
summary of product characteristics
package leaflet
acetaminophen, dextropropoxyphene, drug combination
dextropropoxyphene
capsules

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66894490
2012
France
summary of product characteristics
package leaflet
acetaminophen, dextropropoxyphene, drug combination
capsules
dextropropoxyphene

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69223112
2012
France
summary of product characteristics
package leaflet
acetaminophen, dextropropoxyphene, drug combination
capsules
dextropropoxyphene

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66993606
2012
France
summary of product characteristics
package leaflet
acetaminophen, dextropropoxyphene, drug combination
capsules
dextropropoxyphene

---
http://www.ansm.sante.fr/Infos-de-securite/Lettres-aux-professionnels-de-sante/Specialites-contenant-du-dextropropoxyphene-retrait-du-marche-le-1er-mars-2011-Lettre-aux-professionnels-de-sante
2011
France
French
france
Safety-Based drug withdrawals
dextropropoxyphene
analgesics, opioid
dextropropoxyphene, comb. excl. psycholeptics
drug combinations
pharmacovigilance note

---
http://www.ansm.sante.fr/Infos-de-securite/Retraits-de-lots-et-de-produits/Specialites-a-base-de-dextopropoxyphene-Retrait-de-produits
http://www.ansm.sante.fr/content/download/32132/421765/version/1/file/rlp-110301-Dxp-Liste.pdf
2011
France
French
dextropropoxyphene
Safety-Based drug withdrawals
analgesics, opioid
acetaminophen, dextropropoxyphene, drug combination
drug combinations
caffeine
acetaminophen
dextropropoxyphene, comb. excl. psycholeptics
pharmacovigilance note

---
http://www.cochrane.org/fr/CD001440
2010
false
true
false
France
treatment outcome
review of literature
french abstract
pain, postoperative
acetaminophen
dextropropoxyphene

---
http://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14597a-fra.php
http://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/16115a-fra.php
2010
Canada
English
French
Cardiotoxicity
canada
dextropropoxyphene
Safety-Based drug withdrawals
analgesics, opioid
dextropropoxyphene
arrhythmias, cardiac
pharmacovigilance note
patient education handout

---
http://www.ansm.sante.fr/Infos-de-securite/Communiques-Points-presse/Medicaments-contenant-du-dextropropoxyphene-Retrait-progressif-de-l-AMM-Communique
2010
France
French
dextropropoxyphene
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acetaminophen, dextropropoxyphene, drug combination
Safety-Based drug withdrawals
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pharmacovigilance note

---
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2010
France
French
capsules
administration, oral
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summary of product characteristics
package leaflet

---
http://www.ansm.sante.fr/Infos-de-securite/Communiques-Points-presse/Medicaments-contenant-du-dextropropoxyphene-nouvelles-donnees-americaines-concernant-le-risque-cardiaque-chez-des-volontaires-sains-Communique
2010
France
French
Cardiotoxicity
dextropropoxyphene
analgesics, opioid
heart diseases
united states
dextropropoxyphene
pharmacovigilance note

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64242272
2008
France
French
administration, oral
acetaminophen, dextropropoxyphene, drug combination
dextropropoxyphene, comb. excl. psycholeptics
acetaminophen, dextropropoxyphene, drug combination
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http://www.has-sante.fr/portail/upload/docs/application/pdf/ct-3099_di-antalvic.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_538043
2007
France
French
evaluation of the transparency committee
capsules
insurance, health, reimbursement
acetaminophen, dextropropoxyphene, drug combination
administration, oral
drug combinations
acetaminophen
dextropropoxyphene
analgesics, opioid
analgesics, non-narcotic
dextropropoxyphene, comb. excl. psycholeptics

---
http://www.has-sante.fr/portail/display.jsp?id=c_537978
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct-2311_propofan.pdf
2007
France
French
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tablets
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central nervous system stimulants
dextropropoxyphene
analgesics, opioid
acetaminophen
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dextropropoxyphene, comb. excl. psycholeptics
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---
http://www.centres-antipoison.net/CCTV/Rapport_CCTV_DXP_2000_2005.pdf
2006
France
scientific and technical information
analgesics
codeine
tramadol
poison control centers
france
dextropropoxyphene

---
http://lecrat.fr/spip.php?page=article&id_article=49
2006
France
French
dextropropoxyphene
analgesics, opioid
dextropropoxyphene
analgesics, opioid
pregnancy
infant, newborn
dextropropoxyphene
drug information

---
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2006
France
French
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acetaminophen, dextropropoxyphene, drug combination
administration, oral
drug combinations
dextropropoxyphene, comb. excl. psycholeptics
acetaminophen, dextropropoxyphene, drug combination
acetaminophen
acetaminophen
dextropropoxyphene
dextropropoxyphene
analgesics, opioid
analgesics, opioid
analgesics, non-narcotic
analgesics, non-narcotic
adult
drug interactions
pregnancy
breast feeding
summary of product characteristics
package leaflet

---
http://www.centres-antipoison.net/CCTV/Rapport_CCTV_DXP_1995_2003.pdf
2005
France
scientific and technical information
poison control centers
france
dextropropoxyphene

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