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Preferred Label : fluorouracil;

MeSH definition : A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.;

CISMeF synonym : pharmacia brand of fluorouracil;

MeSH synonym : 5-fu; 5 fluorouracil; 5-fluorouracil; fluoruracil; 5fu; allergan brand of fluorouracil; fluorouracil GRY; gry brand of fluorouracil; dakota, fluorouracile; dakota brand of fluorouracil; ferrer brand of fluorouracil; pharmachemie brand of fluorouracil monosodium salt; haemato fu; haemato brand of fluorouracil; neocorp brand of fluorouracil; onkoworks brand of fluorouracil; ribosepharm brand of fluorouracil; 5 fluorouracil biosyn; biosyn brand of fluorouracil; 5 FU lederle; riemser brand of fluorouracil; 5 FU medac; medac brand of fluorouracil; 5 HU hexal; hexal brand of fluorouracil; teva brand of fluorouracil; fluorouracil teva brand; dermik brand of fluorouracil; dermatech brand of fluorouracil; roche brand of fluorouracil; Fluoro-Uracile ICN; fluoro uracile ICN; ICN brand of fluorouracil; CSP brand of fluorouracil; efudex; flurodex;

MeSH hyponym : adrucil; fluorouracil mononitrate; onkofluor; Fluorouracil-GRY; fluorouracilo ferrer far; fluorouracil potassium salt; fluorouracile dakota; efudix; 5-HU hexal; neofluor; 5-FU lederle; 5-Fluorouracil-biosyn; 5-FU medac; carac; fluorouracil monosodium salt; haemato-fu; fluoroplex; fluracedyl; fluorouracil monopotassium salt; ribofluor;

Is substance : O;

UNII : U3P01618RT;

Registry Number MeSH : 51-21-8; U3P01618RT;

MeSH CAS label : 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-;

MeSH Related Number : fluorouracil mononitrate; fluorouracil monopotassium salt; fluorouracil monosodium salt; fluorouracil potassium salt; 10318-20-4 (mono-Na salt); 51-21-8 (Fluorouracil); 57050-04-1 (K salt); 57172-36-8 (mononitrate); 68021-61-4 (mono-K salt);

Related CAS MeSH : 57172-36-8 (Fluorouracil mononitrate); 68021-61-4 (Fluorouracil monopotassium salt); 10318-20-4 (Fluorouracil monosodium salt); 57050-04-1 (Fluorouracil potassium salt);

Codes EINECS : 200-085-6;

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A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.

N1-VALIDE
http://www.unicancer.fr/sites/default/files/guidelines_gpco-unicancer_dpd_et_fluoropyrimidines.pdf
2016
false
false
false
France
French
dihydropyrimidine dehydrogenase deficiency
mass screening
fluorouracil
patient safety
fluorouracil
Capecitabine
capecitabine
antimetabolites, antineoplastic
practice guideline
fluorouracil
fluorouracil
antimetabolites, antineoplastic
Capecitabine
Capecitabine
dihydropyrimidine dehydrogenase deficiency
genetic screening
france
continuity of patient care
genetic testing

---
http://www.has-sante.fr/portail/jcms/c_2565124/fr/efudix
http://www.has-sante.fr/portail/jcms/c_400913/fr/efudix-5-pour-cent-creme-tube-de-20-g-code-cip-321-843-2
2015
false
France
French
queyrat's erythroplasia
antimetabolites
antimetabolites, antineoplastic
insurance, health, reimbursement
fluorouracil
keratosis, actinic
condylomata acuminata
bowen's disease
erythroplasia
treatment outcome
administration, topical
fluorouracil
evaluation of the transparency committee

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=62990833
2014
false
false
false
France
French
summary of product characteristics
package leaflet
seborrhea sicca
tablets
pill, nos
capecitabine
compression, nos
dandruff
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://www.omeditbretagne.fr/lrportal/documents/138946/147010/xeloda-v1_7pat.pdf/3f49dfa9-a302-40f3-9c5b-f84485c74c72
2014
false
false
false
France
French
guidelines for drug use
patients guideline
capecitabine
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://www.omeditbretagne.fr/lrportal/documents/138946/147512/xeloda-v1_7pro.pdf/dbdbc1f0-f9dd-477f-bf9d-91a596c33a64
2014
false
false
false
France
French
guidelines for drug use
capecitabine
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=69087947
2014
false
false
false
France
French
package leaflet
summary of product characteristics
dandruff
pill, nos
compression, nos
tablets
seborrhea sicca
capecitabine
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=65502762
2014
false
false
false
France
French
summary of product characteristics
capecitabine
tablets
seborrhea sicca
dandruff
pill, nos
compression, nos
capecitabine
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=65970775
2014
false
false
false
France
French
summary of product characteristics
pill, nos
capecitabine
seborrhea sicca
capecitabine
dandruff
tablets
compression, nos
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=63611923
2014
false
false
false
France
French
summary of product characteristics
dandruff
seborrhea sicca
capecitabine
capecitabine
compression, nos
tablets
pill, nos
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/afficheGroupeGene.php?idGrp=1094
2014
false
false
false
France
French
drug information
dandruff
generic drug, nos
capecitabine
pill, nos
waiting lists
seborrhea sicca
capecitabine
compression, nos
tablets
drugs, generic
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=61673260
2014
false
false
false
France
French
summary of product characteristics
pill, nos
capecitabine
dandruff
tablets
compression, nos
capecitabine
seborrhea sicca
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/afficheGroupeGene.php?idGrp=1095
2014
false
false
false
France
French
drug information
tablets
compression, nos
seborrhea sicca
generic drug, nos
dandruff
drugs, generic
capecitabine
pill, nos
waiting lists
capecitabine
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=65248246
2014
false
false
false
France
French
summary of product characteristics
pill, nos
capecitabine
dandruff
tablets
capecitabine
compression, nos
seborrhea sicca
dandruff
deoxycytidine
fluorouracil

---
http://www.cochrane.org/fr/CD001132/le-5-fluorouracil-par-rapport-a-un-placebo-ou-a-labsence-dintervention-pendant-ou-apres-la-chirurgie-du-glaucome
false
false
false
France
review of literature
french abstract
fluorouracil
glaucoma
treatment outcome
wound healing
trabeculectomy

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=64933293
2014
false
false
false
France
French
summary of product characteristics
capecitabine
dandruff
seborrhea sicca
capecitabine
compression, nos
pill, nos
tablets
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=69309579
2014
false
false
false
France
French
summary of product characteristics
tablets
seborrhea sicca
capecitabine
pill, nos
dandruff
capecitabine
compression, nos
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=66104989
2014
false
false
false
France
French
summary of product characteristics
capecitabine
seborrhea sicca
pill, nos
dandruff
tablets
compression, nos
capecitabine
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=62969369
2014
false
false
false
France
French
summary of product characteristics
dandruff
seborrhea sicca
pill, nos
tablets
capecitabine
compression, nos
capecitabine
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=60044987
2014
false
false
false
France
French
summary of product characteristics
compression, nos
tablets
dandruff
capecitabine
pill, nos
capecitabine
seborrhea sicca
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=65982788
2014
false
false
false
France
French
summary of product characteristics
capecitabine
dandruff
capecitabine
compression, nos
seborrhea sicca
tablets
pill, nos
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=69475597
2014
false
false
false
France
French
summary of product characteristics
pill, nos
capecitabine
compression, nos
tablets
dandruff
seborrhea sicca
capecitabine
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=69139187
2014
false
false
false
France
French
summary of product characteristics
tablets
compression, nos
capecitabine
pill, nos
seborrhea sicca
capecitabine
dandruff
dandruff
deoxycytidine
fluorouracil

---
N2-AUTOINDEXEE
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=61174695
2014
false
false
false
France
French
summary of product characteristics
capecitabine
dandruff
capecitabine
tablets
seborrhea sicca
compression, nos
pill, nos
dandruff
deoxycytidine
fluorouracil

---
http://www.cochrane.org/fr/CD006421
2013
France
French
review of literature
meta-analysis
heparin, low-molecular-weight
anticoagulants
intravitreal injections
fluorouracil
vitreoretinopathy, proliferative
postoperative complications
retinal detachment
ophthalmologic surgical procedures
comparative study
treatment outcome
anticoagulotherapy

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69118428
2012
France
summary of product characteristics
package leaflet
fluorouracil

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67294648
2012
France
summary of product characteristics
package leaflet
fluorouracil

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65502207
2012
France
summary of product characteristics
package leaflet
fluorouracil

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63616817
2012
France
summary of product characteristics
package leaflet
fluorouracil

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64590923
2012
France
summary of product characteristics
package leaflet
fluorouracil

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61146475
2012
France
summary of product characteristics
package leaflet
fluorouracil

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65424609
2012
France
summary of product characteristics
package leaflet
fluorouracil

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68136850
2012
France
summary of product characteristics
package leaflet
fluorouracil

---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=217064
2011
France
scientific and technical information
fluorouracil
drug overdose

---
http://fr.cancercare.on.ca/CCO_DrugFormulary/pages/DfPdfContent.aspx?cat=MIS&name=fluorouracil%28Injection%29%20%28pour%20le%20patient%29
2011
Canada
French
fluorouracil
fluorouracil
drug interactions
fluorouracil
fluorouracil
fluorouracil
neoplasms
antimetabolites, antineoplastic
antimetabolites, antineoplastic
antimetabolites, antineoplastic
antimetabolites, antineoplastic
drug information
patient education handout

---
https://www.inspq.qc.ca/toxicologie-clinique/le-triacetate-d-uridine-un-nouvel-antidote-pour-le-traitement-de-l-intoxication-au-5-fluorouracil
2011
false
Canada
French
journal article
PN 401
antidotes
poisoning
fluorouracil
uridine

---
http://www.oncomip.org/fr/dldoc/?t=recommandations&f=doc1&d=195&h=276209b85472fa345bced7a36e6238ae
2011
France
French
patients guideline
drug information
antineoplastic combined chemotherapy protocols
FEC protocol
infusions, intravenous
antineoplastic agents
cyclophosphamide
epirubicin
fluorouracil

---
http://www.oncomip.org/fr/dldoc/?t=recommandations&f=doc1&d=196&h=1d66939a150ad1cc3ec1654d07fc371b
2011
France
French
patients guideline
drug information
antineoplastic combined chemotherapy protocols
FEC protocol
cyclophosphamide
epirubicin
fluorouracil
antineoplastic agents
infusions, intravenous

---
http://www.oncorif.fr/images/stories/Documents_a_telecharger/referentiels/digestif/folfox-avastin.pdf
2010
false
France
French
Bevacizumab
antineoplastic combined chemotherapy protocols
fluorouracil
leucovorin
antineoplastic agents
oxaliplatin
organoplatinum compounds
organoplatinum compounds
patient education handout

---
http://www.oncorif.fr/images/stories/Documents_a_telecharger/referentiels/digestif/folfiri-erbitux.pdf
2010
false
France
French
Cetuximab
fluorouracil
irinotecan
camptothecin
leucovorin
antineoplastic combined chemotherapy protocols
antineoplastic agents
camptothecin
patient education handout

---
http://www.oncorif.fr/images/stories/Documents_a_telecharger/referentiels/digestif/lv5fu2.pdf
2010
France
French
fluorouracil
leucovorin
antineoplastic combined chemotherapy protocols
antineoplastic agents
vitamin B complex
infusions, intravenous
patient education handout

---
http://www.oncorif.fr/images/stories/Documents_a_telecharger/referentiels/digestif/folfiri-avastin.pdf
2010
false
France
French
Bevacizumab
fluorouracil
antineoplastic combined chemotherapy protocols
antineoplastic agents
irinotecan
leucovorin
camptothecin
infusions, parenteral
camptothecin
patient education handout

---
http://www.oncorif.fr/images/stories/Documents_a_telecharger/referentiels/digestif/folfiri.pdf
2010
France
French
antineoplastic combined chemotherapy protocols
antineoplastic agents
fluorouracil
leucovorin
irinotecan
camptothecin
infusions, intravenous
IFL protocol
camptothecin
patient education handout

---
http://www.cochrane.org/fr/CD007046
2010
false
true
false
France
fluorouracil
treatment outcome
review of literature
french abstract
colorectal neoplasms

---
http://www.aboutkidshealth.ca/en/healthaz/drugs/pages/fluorouracil-for-injection.aspx?k=fluoro-uracile;+administration+de+m%c3%a9dicaments;+agents+de+chimioth%c3%a9rapie;+cancer;+intraveineuse
http://www.aboutkidshealth.ca/Fr/HealthAZ/Drugs/Pages/Fluorouracil-for-Injection.aspx
2010
Canada
French
English
child
injections
fluorouracil
fluorouracil
antimetabolites, antineoplastic
antimetabolites, antineoplastic
fluorouracil
patient education handout
drug information

---
http://www.cochrane.org/fr/CD006562
2010
false
true
false
France
condylomata acuminata
fluorouracil
treatment outcome
review of literature
french abstract

---
http://www.oncorif.fr/images/stories/Documents_a_telecharger/referentiels/sein/fec.pdf
2010
France
French
fluorouracil
antineoplastic combined chemotherapy protocols
antineoplastic agents
cyclophosphamide
epirubicin
infusions, intravenous
FEC protocol
patient education handout

---
http://www.oncorif.fr/images/stories/Documents_a_telecharger/referentiels/digestif/folfox-erbitux.pdf
2010
false
France
French
Cetuximab
fluorouracil
oxaliplatin
antineoplastic combined chemotherapy protocols
antineoplastic agents
organoplatinum compounds
leucovorin
infusions, parenteral
organoplatinum compounds
patient education handout

---
http://www.oncorif.fr/images/stories/Documents_a_telecharger/referentiels/digestif/folfox.pdf
2010
France
French
antineoplastic combined chemotherapy protocols
fluorouracil
oxaliplatin
antineoplastic agents
organoplatinum compounds
infusions, intravenous
antineoplastic agents
Folfox protocol
organoplatinum compounds
patient education handout

---
http://www.has-sante.fr/portail/display.jsp?id=c_399791
2003
France
evaluation of the transparency committee
fluorouracil

---
E-mail
05/12/2016


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