Veille documentaire MTPH

Médecine du travail du personnel hospitalier

Field application of SPME as a novel tool for occupational exposure assessment with inhalational anesthetics

Auteur     Mohammad Javad Zare Sakhvidi
Auteur     AbdulRahman Bahrami
Auteur     Alireza Ghiasvand
Auteur     Hossein Mahjub
Auteur     Ludovic Tuduri
Résumé     Occupational exposure to inhalational anesthetics occurs routinely in operating rooms. It could induce serious health hazards and diseases. This exposure assessment is a crucial step in determining risks. In this study, a pen-shaped holder for solid-phase microextraction (SPME) sampler was successfully applied as a time-weighted average sampling tool for workshift exposure assessment of operation room staff to halothane. It proved to be very convenient for use in occupational environments such as operation rooms. Samples were analyzed by a gas chromatography-mass spectrometry. The validity of the SPME method was checked in real-world conditions with Occupational Safety and Health Administration (OSHA) 103 standard method for the determination of inhalational anesthetics. A good agreement between OSHA 103 and SPME methods was obtained and results demonstrated no statistically significant differences in anesthetic concentrations determined by the two analytical methods (p ≥ 0.05). It is concluded that SPME in retracted mode could successfully be applied in occupational exposure assessment purposes.
Publication     Environmental monitoring and assessment
Volume     184
Numéro     11
Pages     6483-6490
Date     Nov 2012

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doi:10.1007/s10661-011-2434-7

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