Veille documentaire MTPH

Auteur Nicole Zitterkopf Khoury
Auteur Matthew J Binnicker
Auteur Nancy L Wengenack
Auteur Timothy R Aksamit
Auteur William G Buchta
Auteur Robin G Molella
Résumé OBJECTIVE:: Determine the performance of an interferon-γ release assay in a health care occupational surveillance program. METHODS:: From January 11, 2005, through January 31, 2006, all new employees (n = 652) undergoing standard, preemployment evaluation at Mayo Clinic, Rochester, Minnesota were evaluated for tuberculosis using a standard process of symptom screening combined with tuberculin skin test (TST) and QuantiFERON-TB Gold test (QFT-G). RESULTS:: Comparing the results of QFT-G directly to TST, QFT-G showed an overall agreement of 92.5%. CONCLUSIONS:: False-positive TST were the most significant issue affecting agreement, and in a low-tuberculosis prevalence population, the need for an effective strategy offering low false-positive results may be best met by combining the TST with QFT-G.
Publication Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine
Date Feb 21, 2011