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Infez Med. 2007 Sep;15(3):187-90.
Clinical case of seroconversion for syphilis following a needlestick injury: why not take a prophylaxis?
Franco A, Aprea L, Dell’Isola C, Faella FS, Felaco FM, Manzillo E, Martucci F, Pizzella T, Sansone M, Simioli F, Simioli S, Izzo CM.
Infectious Diseases Hospital D. Cotugno, Naples, Italy.
A 47-year-old woman was pricked accidentally with a needle previously used for a neurosyphilitic man. At day 0 she had no positive laboratory results for the infection, while the source, at day 1, had TPHA positive, but no post-exposure prophylaxis (PEP) against syphilis was prescribed. The subject missed the day 30 follow-up, and underwent our visit at day 90, when she showed no clinical signs, but she seroconverted (VDRL = positive 1/2; TPHA = positive 1/320; FTA-Abs IgG and IgM = present). She started antibiotic therapy, and currently her serological status is VDRL = positive 1/2, TPHA = positive 1/160, FTA-Abs IgM = negative.
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